Division of “Molecular Biology, Proteomics and Metabolomic”
Faculty
Services
Courses & Short term Trainings
Research
Expansion plan
Division of “Molecular Biology, Proteomics and Metabolomic”
Vision statement: The Division looks forward to serve as a centre of excellence, committed to basic and translational research in healthcare and diagnostics. The activities will be dedicated to improve quality of life of individuals suffering from various challenges of today’s medical practices. Division will cater to research and diagnostics facilities for genetic diseases using genetic mutation based assay for different cancer, neurological disorder, Inborn errors, and metabolic disorder. Our future prospect is to be the best in the world of holistic wellbeing. Making preventive, predictive and diagnostic healthcare accessible to everyone.
Mission statement: It promises to provide quality laboratory services in a timely, accurate, and efficient manner for optimal patient outcome and health. Our dedication to excellence pushes our team to deliver consistent, current, high quality results, exemplary research and diagnostics resources today and anticipating needs of tomorrow.
Faculty
| Photo | Name & Qualifications | Designation | Areas of Interest | Email ID / ORCID ID / Research-gate Page |
|---|---|---|---|---|
 | Dr. Nilotpal Chowdhury MBBS, MD Pathology | Member | Clinical :- Breast Pathology,Cytopathology, Genomics, Gynecological Pathology, Uropathology, Laboratory hematology Research :- Breast Pathology,Cytopathology, Genomics, Gynecological Pathology, Uropathology, Laboratory hematology, Molecular Pathology, Statistics | nilotpal.path@aiimsrishikesh.edu.in http://orcid.org/0000-0002-3178-2039 |
 | Dr. Prashant Joshi MBBS, MD Pathology | Member Secretary | Clinical :- Histopathology, Cytopathology Research :- Bone and Soft Tissue neoplasia | prashantj.path@aiimsrishikesh.edu.in http://orcid.org/0000-0003-4112-3923 |
| Photo | Name & Qualifications | Designation | Areas of Interest | Email ID / ORCID ID / Research-gate Page |
|---|
Services
Services Available in the department:
UPCOMING SERVICES:
Ready-to-start Standardised, validated and completed tests:
- 3.k-RAS
- HLA B27 strip assay
- Polymerase Chain Reaction (PCR) based assay- strip assay
- EGFR 28 mutation strip assay
- Flourescent in-situ Hybridisation (FISH)- (Soft tissue)
- ERBB2(her2neu)
- Ewing Sarcoma (EWSR1)
- Synovial Sarcoma (SS18)
- Lung Adca(ALK)
- Lung adca (Ros1)
- Glioma (1p;19q del)
- Myxoid liposarcoma (DDIT3)
- Aneurysmal bone cyst (USP6)
- Flourescent in-situ Hybridisation (FISH)-(Hematology)
- CML (BCR-ABL)
- APML (PML-RARA)
- MDS (5q del)
- ALL (ETV6)
- Research in the department: Facilities available for the research
Cell culture laboratory: An in-use facility available for maintainance of cell lines of various disease like neurological disorders, breast cancer, liver cancer, metabolic diseases and also primary cells grown from tissues, blood and other body fluids. In future we plan to expand the cell culture facility for stem cell research and regenerative medicine as well.
Fluorescent In- situ Hybridization laboratory: Tissue and hematological FISH have been standardized for a number of malignancies for eg: CML, Breast cancer etc to name a few.
PCR lab
Quantitative Real Time-PCR lab
Bio Banking facility: Biobank supplies high quality clinically annotated human samples to researchers in academic and institution to foster medically relevant research discoveries and improve treatment option. This is most important tool for future research. This is the first facility in north India which provides uniform temperature and maintain stability of protein, DNA and RNA in blood, tissue and other biological fluids.
Clinical Metabolomics Laboratory
Introduction: Establishment of Clinical Metabolomics Laboratory is planned, offering custom metabolomics for researchers at AIIMS Rishikesh and eventually investigators of scientific community even outside AIIMS Rishikesh. This would be a Liquid Chromatography – Mass spectrometry (LC-MSMS) with triple quadruple system having Ion Trap Facility. This metabolomics lab would offer targeted methods for known and unknown metabolite identification and quantification.
Expected Benefits: Development of this facility would ensure thriving of research output and milieu. Thus serving as a platform to enhance research which is a mandate of our Institute. “Clinical Metabolomics Laboratory” would offer testing facilities for wide variety of molecules, supporting varied research. Facility would primarily focus on Liquid Chromatography – Mass spectrometry (LCMSMS) with triple quadruple system having Ion Trap Facility.
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Courses & Short term Trainings
| Name of the course | Curriculum | Duration of course | Present number of students | Objectives/ brief description of the course |
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Research
Projects
| Title | Co-PI | Principal Investigator | Collaboration, if any (Department and institute) | Funding Agency | Projects Status |
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Expansion plan
Expansion planned for the future:
- Clinical Services: Planning to start the Molecular diagnostic tests for tumors and malignancies; Karyotyping by CBA method is on the way of standardization for screening of inborn errors, various malignancies and congenital anomalies.
- Academics and teaching: None as of now
- Research: A PhD research project is ongoing on molecular screening of genes in Breast Cancer