Division of “Molecular Biology, Proteomics and Metabolomic”

Photo Name & Qualifications Designation Areas of Interest Email ID / ORCID ID / Research-gate Page
Dr. Nilotpal Chowdhury
MBBS, MD Pathology
MemberClinical :- Breast Pathology,Cytopathology, Genomics, Gynecological Pathology, Uropathology, Laboratory hematology

Research :- Breast Pathology,Cytopathology, Genomics, Gynecological Pathology, Uropathology, Laboratory hematology, Molecular Pathology, Statistics
nilotpal.path@aiimsrishikesh.edu.in

http://orcid.org/0000-0002-3178-2039
Dr. Prashant Joshi
MBBS, MD Pathology
Member SecretaryClinical :- Histopathology, Cytopathology

Research :- Bone and Soft Tissue neoplasia
prashantj.path@aiimsrishikesh.edu.in

http://orcid.org/0000-0003-4112-3923
Photo Name & Qualifications Designation Areas of Interest Email ID / ORCID ID / Research-gate Page

Services Available in the department:

UPCOMING SERVICES:

Ready-to-start Standardised, validated and completed tests:

  • 3.k-RAS
  • HLA B27 strip assay
  • Polymerase Chain Reaction (PCR) based assay- strip assay
    • EGFR 28 mutation strip assay
  • Flourescent in-situ Hybridisation (FISH)- (Soft tissue)
    • ERBB2(her2neu)
    • Ewing Sarcoma (EWSR1)
    • Synovial Sarcoma (SS18)
    • Lung Adca(ALK)
    • Lung adca (Ros1)
    • Glioma (1p;19q del)
    • Myxoid liposarcoma (DDIT3)
    • Aneurysmal bone cyst (USP6)
  • Flourescent in-situ Hybridisation (FISH)-(Hematology)
    • CML (BCR-ABL)
    • APML (PML-RARA)
    • MDS (5q del)
    • ALL (ETV6)
  • Research in the department: Facilities available for the research

Cell culture laboratory: An in-use facility available for maintainance of cell lines of various disease like neurological disorders, breast cancer, liver cancer, metabolic diseases and also primary cells grown from tissues, blood and other body fluids. In future we plan to expand the cell culture facility for stem cell research and regenerative medicine as well.

Fluorescent In- situ Hybridization laboratory: Tissue and hematological FISH have been standardized for a number of malignancies for eg: CML, Breast cancer etc to name a few.

PCR lab

Quantitative Real Time-PCR lab

Bio Banking facility: Biobank supplies high quality clinically annotated human samples to researchers in academic and institution to foster medically relevant research discoveries and improve treatment option. This is most important tool for future research. This is the first facility in north India which provides uniform temperature and maintain stability of protein, DNA and RNA in blood, tissue and other biological fluids.

Clinical Metabolomics Laboratory

Introduction: Establishment of Clinical Metabolomics Laboratory is planned, offering custom metabolomics for researchers at AIIMS Rishikesh and eventually investigators of scientific community even outside AIIMS Rishikesh. This would be a Liquid Chromatography – Mass spectrometry (LC-MSMS) with triple quadruple system having Ion Trap Facility. This metabolomics lab would offer targeted methods for known and unknown metabolite identification and quantification.

Expected Benefits: Development of this facility would ensure thriving of research output and milieu. Thus serving as a platform to enhance research which is a mandate of our Institute. “Clinical Metabolomics Laboratory” would offer testing facilities for wide variety of molecules, supporting varied research. Facility would primarily focus on Liquid Chromatography – Mass spectrometry (LCMSMS) with triple quadruple system having Ion Trap Facility.

Name of the course Curriculum Duration of course Present number of students Objectives/ brief description of the course

Projects

Title Co-PI Principal Investigator Collaboration, if any (Department and institute) Funding Agency Projects Status

Expansion planned for the future:

  • Clinical Services: Planning to start the Molecular diagnostic tests for tumors and malignancies; Karyotyping by CBA method is on the way of standardization for screening of inborn errors, various malignancies and congenital anomalies.
  • Academics and teaching: None as of now
  • Research: A PhD research project is ongoing on molecular screening of genes in Breast Cancer
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